Global Plasminogen Market Growth 2021-2026


Jul, 2021 | Report ID: 203876 | 91 | Pharmaceuticals and Healthcare

According to this latest study, the 2021 growth of Plasminogen will have significant change from previous year. By the most conservative estimates of global Plasminogen market size (most likely outcome) will be a year-over-year revenue growth rate of XX% in 2021, from US$ 12900 million in 2020. Over the next five years the Plasminogen market will register a 5.0% CAGR in terms of revenue, the global market size will reach US$ 15670 million by 2026.

This report presents a comprehensive overview, market shares, and growth opportunities of Plasminogen market by product type, application, key manufacturers and key regions and countries.

Segmentation by type: breakdown data from 2016 to 2021, in Section 2.3; and forecast to 2026 in section 11.7.

Intravenous Injection

Eye Drops

Segmentation by application: breakdown data from 2016 to 2021, in Section 2.4; and forecast to 2026 in section 11.8.

Ligneous Conjunctivitis

Diabetic Foot

Wound Healing

Others

This report also splits the market by region: Breakdown data in Chapter 4, 5, 6, 7 and 8.

Americas

United States

Canada

Mexico

Brazil

APAC

China

Japan

Korea

Southeast Asia

India

Australia

Europe

Germany

France

UK

Italy

Russia

Middle East & Africa

Egypt

South Africa

Israel

Turkey

GCC Countries

The report also presents the market competition landscape and a corresponding detailed analysis of the major vendor/manufacturers in the market. The key manufacturers covered in this report: Breakdown data in Chapter 3.

Kedrion

Prometic

Genentech (Roche)

Boehringer Ingelheim

Kyowa Hakko Kirin

Omeros Corporation


Frequently Asked Questions

The base year for the study has been considered 2019, historic year 2014 and 2018, the forecast period considered is from 2020 to 2027. The regions analyzed for the market include North America, Europe, South America, Asia Pacific, and Middle East and Africa. These regions are further analyzed at the country-level. The study also includes attractiveness analysis of type, application and regions which are benchmarked based on their market size, growth rate and attractiveness in terms of present and future opportunity for understanding the future growth of the market.

Market is segmented on the basis:

  • By Type
  • By Application
  • By Region
  • By Country
  • By Manufacturer

The report offers in-depth analysis of driving factors, opportunities, restraints, and challenges for gaining the key insight of the market. The report emphasizes on all the key trends that play a vital role in the enlargement of the market from 2019 to 2026.

The report provides company profile of the key players operating in the market and a comparative analysis based on their business overviews industry offering, segment market share, regional presence, business strategies, innovations, mergers & acquisitions, recent developments, joint venture, collaborations, partnerships, SWOT analysis, and key financial information.

1 Scope of the Report

1.1 Market Introduction

1.2 Years Considered

1.3 Research Objectives

1.4 Market Research Methodology

1.5 Research Process and Data Source

1.6 Economic Indicators

1.7 Currency Considered

2 Executive Summary

2.1 World Market Overview

2.1.1 Global Plasminogen Consumption 2016-2026

2.1.2 Plasminogen Consumption CAGR by Region

2.2 Plasminogen Segment by Type

2.2.1 Intravenous Injection

2.2.2 Eye Drops

2.3 Plasminogen Sales by Type

2.3.1 Global Plasminogen Sales Market Share by Type (2016-2021)

2.3.2 Global Plasminogen Revenue and Market Share by Type (2016-2021)

2.3.3 Global Plasminogen Sale Price by Type (2016-2021)

2.4 Plasminogen Segment by Application

2.4.1 Ligneous Conjunctivitis

2.4.2 Diabetic Foot

2.4.3 Wound Healing

2.4.4 Others

2.5 Plasminogen Sales by Application

2.5.1 Global Plasminogen Sale Market Share by Application (2016-2021)

2.5.2 Global Plasminogen Revenue and Market Share by Application (2016-2021)

2.5.3 Global Plasminogen Sale Price by Application (2016-2021)

3 Global Plasminogen by Company

3.1 Global Plasminogen Sales Market Share by Company

3.1.1 Global Plasminogen Sales by Company (2019-2021)

3.1.2 Global Plasminogen Sales Market Share by Company (2019-2021)

3.2 Global Plasminogen Revenue Market Share by Company

3.2.1 Global Plasminogen Revenue by Company (2019-2021)

3.2.2 Global Plasminogen Revenue Market Share by Company (2019-2021)

3.3 Global Plasminogen Sale Price by Company

3.4 Global Manufacturers Plasminogen Producing Area Distribution, Sales Area, Product Type

3.4.1 Key Manufacturers Plasminogen Product Location Distribution

3.4.2 Players Plasminogen Products Offered

3.5 Market Concentration Rate Analysis

3.5.1 Competition Landscape Analysis

3.5.2 Concentration Ratio (CR3, CR5 and CR10) & (2019-2021)

3.6 New Products and Potential Entrants

3.7 Mergers & Acquisitions, Expansion

4 Plasminogen by Region

4.1 Global Plasminogen by Region

4.1.1 Global Plasminogen Sales by Region

4.1.2 Global Plasminogen Revenue by Region

4.2 Americas Plasminogen Sales Growth

4.3 APAC Plasminogen Sales Growth

4.4 Europe Plasminogen Sales Growth

4.5 Middle East & Africa Plasminogen Sales Growth

5 Americas

5.1 Americas Plasminogen Sales by Country

5.1.1 Americas Plasminogen Sales by Country (2016-2021)

5.1.2 Americas Plasminogen Revenue by Country (2016-2021)

5.2 Americas Plasminogen Sales by Type

5.3 Americas Plasminogen Sales by Application

5.4 United States

5.5 Canada

5.6 Mexico

5.7 Brazil

6 APAC

6.1 APAC Plasminogen Sales by Region

6.1.1 APAC Plasminogen Sales by Region (2016-2021)

6.1.2 APAC Plasminogen Revenue by Region (2016-2021)

6.2 APAC Plasminogen Sales by Type

6.3 APAC Plasminogen Sales by Application

6.4 China

6.5 Japan

6.6 Korea

6.7 Southeast Asia

6.8 India

6.9 Australia

7 Europe

7.1 Europe Plasminogen by Country

7.1.1 Europe Plasminogen Sales by Country (2016-2021)

7.1.2 Europe Plasminogen Revenue by Country (2016-2021)

7.2 Europe Plasminogen Sales by Type

7.3 Europe Plasminogen Sales by Application

7.4 Germany

7.5 France

7.6 UK

7.7 Italy

7.8 Russia

8 Middle East & Africa

8.1 Middle East & Africa Plasminogen by Country

8.1.1 Middle East & Africa Plasminogen Sales by Country (2016-2021)

8.1.2 Middle East & Africa Plasminogen Revenue by Country (2016-2021)

8.2 Middle East & Africa Plasminogen Sales by Type

8.3 Middle East & Africa Plasminogen Sales by Application

8.4 Egypt

8.5 South Africa

8.6 Israel

8.7 Turkey

8.8 GCC Country

9 Market Drivers, Challenges and Trends

9.1 Market Drivers and Impact

9.1.1 Growing Demand from Key Regions

9.1.2 Growing Demand from Key Applications and Potential Industries

9.2 Market Challenges and Impact

9.3 Market Trends

10 Marketing, Distributors and Customer

10.1 Sales Channel

10.1.1 Direct Channels

10.1.2 Indirect Channels

10.2 Plasminogen Distributors

10.3 Plasminogen Customer

11 Global Plasminogen Market Forecast

11.1 Global Plasminogen Forecast by Region

11.1.1 Global Plasminogen Forecast by Regions (2021-2026)

11.2.2 Global Plasminogen Revenue Forecast by Regions (2021-2026)

11.2 Americas Forecast by Country

11.3 APAC Forecast by Region

11.4 Europe Forecast by Country

11.5 Middle East & Africa Forecast by Country

11.6 Global Plasminogen Forecast by Type

11.7 Global Plasminogen Forecast by Application

12 Key Players Analysis

12.1 Kedrion

12.1.1 Kedrion Company Information

12.1.2 Kedrion Plasminogen Product Offered

12.1.3 Kedrion Plasminogen Sales, Revenue, Price and Gross Margin (2019-2021)

12.1.4 Kedrion Main Business Overview

12.1.5 Kedrion Latest Developments

12.2 Prometic

12.2.1 Prometic Company Information

12.2.2 Prometic Plasminogen Product Offered

12.2.3 Prometic Plasminogen Sales, Revenue, Price and Gross Margin (2019-2021)

12.2.4 Prometic Main Business Overview

12.2.5 Prometic Latest Developments

12.3 Genentech (Roche)

12.3.1 Genentech (Roche) Company Information

12.3.2 Genentech (Roche) Plasminogen Product Offered

12.3.3 Genentech (Roche) Plasminogen Sales, Revenue, Price and Gross Margin (2019-2021)

12.3.4 Genentech (Roche) Main Business Overview

12.3.5 Genentech (Roche) Latest Developments

12.4 Boehringer Ingelheim

12.4.1 Boehringer Ingelheim Company Information

12.4.2 Boehringer Ingelheim Plasminogen Product Offered

12.4.3 Boehringer Ingelheim Plasminogen Sales, Revenue, Price and Gross Margin (2019-2021)

12.4.4 Boehringer Ingelheim Main Business Overview

12.4.5 Boehringer Ingelheim Latest Developments

12.5 Kyowa Hakko Kirin

12.5.1 Kyowa Hakko Kirin Company Information

12.5.2 Kyowa Hakko Kirin Plasminogen Product Offered

12.5.3 Kyowa Hakko Kirin Plasminogen Sales, Revenue, Price and Gross Margin (2019-2021)

12.5.4 Kyowa Hakko Kirin Main Business Overview

12.5.5 Kyowa Hakko Kirin Latest Developments

12.6 Omeros Corporation

12.6.1 Omeros Corporation Company Information

12.6.2 Omeros Corporation Plasminogen Product Offered

12.6.3 Omeros Corporation Plasminogen Sales, Revenue, Price and Gross Margin (2019-2021)

12.6.4 Omeros Corporation Main Business Overview

12.6.5 Omeros Corporation Latest Developments

...

13 Research Findings and Conclusion

List of Tables

Table 1. Plasminogen Consumption CAGR by Region (2020-2026) & ($ Millions)

Table 2. Major Players of Intravenous Injection

Table 3. Major Players of Eye Drops

Table 4. Global Plasminogen Sales by Type (2016-2021) & (MT)

Table 5. Global Plasminogen Sales Market Share by Type (2016-2021)

Table 6. Global Plasminogen Revenue by Type (2016-2021) & ($ million)

Table 7. Global Plasminogen Revenue Market Share by Type (2016-2021)

Table 8. Global Plasminogen Sale Price by Type (2016-2021)

Table 9. Global Plasminogen Sales by Application (2016-2021) & (MT)

Table 10. Global Plasminogen Sales Market Share by Application (2016-2021)

Table 11. Global Plasminogen Value by Application (2016-2021)

Table 12. Global Plasminogen Revenue Market Share by Application (2016-2021)

Table 13. Global Plasminogen Sale Price by Application (2016-2021)

Table 14. Global Plasminogen Sales by Company (2019-2021) & (MT)

Table 15. Global Plasminogen Sales Market Share by Company (2019-2021)

Table 16. Global Plasminogen Revenue by Company (2019-2021) ($ Millions)

Table 17. Global Plasminogen Revenue Market Share by Company (2019-2021)

Table 18. Global Plasminogen Sale Price by Company (2019-2021)

Table 19. Key Manufacturers Plasminogen Producing Area Distribution and Sales Area

Table 20. Players Plasminogen Products Offered

Table 21. Plasminogen Concentration Ratio (CR3, CR5 and CR10) & (2019-2021)

Table 22. New Products and Potential Entrants

Table 23. Mergers & Acquisitions, Expansion

Table 24. Global Plasminogen Sales by Region (2016-2021) (MT)

Table 25. Global Plasminogen Sales Market Share by Region (2016-2021)

Table 26. Global Plasminogen Revenue by Region (2016-2021) & ($ Millions)

Table 27. Global Plasminogen Revenue Market Share by Region (2016-2021)

Table 28. Americas Plasminogen Sales by Country (2016-2021) & (MT)

Table 29. Americas Plasminogen Sales Market Share by Country (2016-2021)

Table 30. Americas Plasminogen Revenue by Country (2016-2021) & ($ Millions)

Table 31. Americas Plasminogen Revenue Market Share by Country (2016-2021)

Table 32. Americas Plasminogen Sales by Type (2016-2021) & (MT)

Table 33. Americas Plasminogen Sales Market Share by Type (2016-2021)

Table 34. Americas Plasminogen Sales by Application (2016-2021) & (MT)

Table 35. Americas Plasminogen Sales Market Share by Application (2016-2021)

Table 36. APAC Plasminogen Sales by Region (2016-2021) & (MT)

Table 37. APAC Plasminogen Sales Market Share by Region (2016-2021)

Table 38. APAC Plasminogen Revenue by Region (2016-2021) & ($ Millions)

Table 39. APAC Plasminogen Revenue Market Share by Region (2016-2021)

Table 40. APAC Plasminogen Sales by Type (2016-2021) & (MT)

Table 41. APAC Plasminogen Sales Market Share by Type (2016-2021)

Table 42. APAC Plasminogen Sales by Application (2016-2021) & (MT)

Table 43. APAC Plasminogen Sales Market Share by Application (2016-2021)

Table 44. Europe Plasminogen Sales by Country (2016-2021) & (MT)

Table 45. Europe Plasminogen Sales Market Share by Country (2016-2021)

Table 46. Europe Plasminogen Revenue by Country (2016-2021) & ($ Millions)

Table 47. Europe Plasminogen Revenue Market Share by Country (2016-2021)

Table 48. Europe Plasminogen Sales by Type (2016-2021) & (MT)

Table 49. Europe Plasminogen Sales Market Share by Type (2016-2021)

Table 50. Europe Plasminogen Sales by Application (2016-2021) & (MT)

Table 51. Europe Plasminogen Sales Market Share by Application (2016-2021)

Table 52. Middle East & Africa Plasminogen Sales by Country (2016-2021) & (MT)

Table 53. Middle East & Africa Plasminogen Sales Market Share by Country (2016-2021)

Table 54. Middle East & Africa Plasminogen Revenue by Country (2016-2021) & ($ Millions)

Table 55. Middle East & Africa Plasminogen Revenue Market Share by Country (2016-2021)

Table 56. Middle East & Africa Plasminogen Sales by Type (2016-2021) & (MT)

Table 57. Middle East & Africa Plasminogen Sales Market Share by Type (2016-2021)

Table 58. Middle East & Africa Plasminogen Sales by Application (2016-2021) & (MT)

Table 59. Middle East & Africa Plasminogen Sales Market Share by Application (2016-2021)

Table 60. Key and Potential Regions of Plasminogen

Table 61. Key Application and Potential Industries of Plasminogen

Table 62. Key Challenges of Plasminogen

Table 63. Key Trends of Plasminogen

Table 64. Plasminogen Distributors List

Table 65. Plasminogen Customer List

Table 66. Global Plasminogen Sales Forecast by Region (2021-2026) & (MT)

Table 67. Global Plasminogen Consumption Market Forecast by Region

Table 68. Global Plasminogen Revenue Forecast by Region (2021-2026) & ($ millions)

Table 69. Global Plasminogen Revenue Market Share Forecast by Region (2021-2026)

Table 70. Americas Plasminogen Sales Forecast by Country (2021-2026) & (MT)

Table 71. Americas Plasminogen Revenue Forecast by Country (2021-2026) & ($ millions)

Table 72. APAC Plasminogen Sales Forecast by Region (2021-2026) & (MT)

Table 73. APAC Plasminogen Revenue Forecast by Region (2021-2026) & ($ millions)

Table 74. Europe Plasminogen Sales Forecast by Country (2021-2026) & (MT)

Table 75. Europe Plasminogen Revenue Forecast by Country (2021-2026) & ($ millions)

Table 76. Middle East & Africa Plasminogen Sales Forecast by Country (2021-2026) & (MT)

Table 77. Middle East & Africa Plasminogen Revenue Forecast by Country (2021-2026) & ($ millions)

Table 78. Global Plasminogen Sales Forecast by Type (2021-2026) & (MT)

Table 79. Global Plasminogen Sales Market Share Forecast by Type (2021-2026)

Table 80. Global Plasminogen Revenue Forecast by Type (2021-2026) & ($ Millions)

Table 81. Global Plasminogen Revenue Market Share Forecast by Type (2021-2026)

Table 82. Global Plasminogen Sales Forecast by Application (2021-2026) & (MT)

Table 83. Global Plasminogen Sales Market Share Forecast by Application (2021-2026)

Table 84. Global Plasminogen Revenue Forecast by Application (2021-2026) & ($ Millions)

Table 85. Global Plasminogen Revenue Market Share Forecast by Application (2021-2026)

Table 86. Kedrion Basic Information, Plasminogen Manufacturing Base, Sales Area and Its Competitors

Table 87. Kedrion Plasminogen Product Offered

Table 88. Kedrion Plasminogen Sales (MT), Revenue ($ Million), Price (USD/MT) and Gross Margin (2019-2021E)

Table 89. Kedrion Main Business

Table 90. Kedrion Latest Developments

Table 91. Prometic Basic Information, Plasminogen Manufacturing Base, Sales Area and Its Competitors

Table 92. Prometic Plasminogen Product Offered

Table 93. Prometic Plasminogen Sales (MT), Revenue ($ Million), Price (USD/MT) and Gross Margin (2019-2021E)

Table 94. Prometic Main Business

Table 95. Prometic Latest Developments

Table 96. Genentech (Roche) Basic Information, Plasminogen Manufacturing Base, Sales Area and Its Competitors

Table 97. Genentech (Roche) Plasminogen Product Offered

Table 98. Genentech (Roche) Plasminogen Sales (MT), Revenue ($ Million), Price (USD/MT) and Gross Margin (2019-2021E)

Table 99. Genentech (Roche) Main Business

Table 100. Genentech (Roche) Latest Developments

Table 101. Boehringer Ingelheim Basic Information, Plasminogen Manufacturing Base, Sales Area and Its Competitors

Table 102. Boehringer Ingelheim Plasminogen Product Offered

Table 103. Boehringer Ingelheim Plasminogen Sales (MT), Revenue ($ Million), Price (USD/MT) and Gross Margin (2019-2021E)

Table 104. Boehringer Ingelheim Main Business

Table 105. Boehringer Ingelheim Latest Developments

Table 106. Kyowa Hakko Kirin Basic Information, Plasminogen Manufacturing Base, Sales Area and Its Competitors

Table 107. Kyowa Hakko Kirin Plasminogen Product Offered

Table 108. Kyowa Hakko Kirin Plasminogen Sales (MT), Revenue ($ Million), Price (USD/MT) and Gross Margin (2019-2021E)

Table 109. Kyowa Hakko Kirin Main Business

Table 110. Kyowa Hakko Kirin Latest Developments

Table 111. Omeros Corporation Basic Information, Plasminogen Manufacturing Base, Sales Area and Its Competitors

Table 112. Omeros Corporation Plasminogen Product Offered

Table 113. Omeros Corporation Plasminogen Sales (MT), Revenue ($ Million), Price (USD/MT) and Gross Margin (2019-2021E)

Table 114. Omeros Corporation Main Business

Table 115. Omeros Corporation Latest Developments

List of Figures

Figure 1. Picture of Plasminogen

Figure 2. Plasminogen Report Years Considered

Figure 3. Research Objectives

Figure 4. Research Methodology

Figure 5. Research Process and Data Source

Figure 6. Global Plasminogen Sales Growth Rate 2016-2026 (MT)

Figure 7. Global Plasminogen Revenue Growth Rate 2016-2026 ($ Millions)

Figure 8. Plasminogen Sales by Region (2021 & 2026) & ($ millions)

Figure 9. Product Picture of Intravenous Injection

Figure 10. Product Picture of Eye Drops

Figure 11. Global Plasminogen Sales Market Share by Type in 2020

Figure 12. Global Plasminogen Revenue Market Share by Type (2016-2021)

Figure 13. Plasminogen Consumed in Ligneous Conjunctivitis

Figure 14. Global Plasminogen Market: Ligneous Conjunctivitis (2016-2021) & (MT)

Figure 15. Plasminogen Consumed in Diabetic Foot

Figure 16. Global Plasminogen Market: Diabetic Foot (2016-2021) & (MT)

Figure 17. Plasminogen Consumed in Wound Healing

Figure 18. Global Plasminogen Market: Wound Healing (2016-2021) & (MT)

Figure 19. Plasminogen Consumed in Others

Figure 20. Global Plasminogen Market: Others (2016-2021) & (MT)

Figure 21. Global Plasminogen Sales Market Share by Application (2016-2021)

Figure 22. Global Plasminogen Revenue Market Share by Application in 2020

Figure 23. Plasminogen Revenue Market by Company in 2020 ($ Million)

Figure 24. Global Plasminogen Revenue Market Share by Company in 2020

Figure 25. Global Plasminogen Sales Market Share by Regions (2016-2021)

Figure 26. Global Plasminogen Revenue Market Share by Region in 2020

Figure 27. Americas Plasminogen Sales 2016-2021 (MT)

Figure 28. Americas Plasminogen Revenue 2016-2021 ($ Millions)

Figure 29. APAC Plasminogen Sales 2016-2021 (MT)

Figure 30. APAC Plasminogen Revenue 2016-2021 ($ Millions)

Figure 31. Europe Plasminogen Sales 2016-2021 (MT)

Figure 32. Europe Plasminogen Revenue 2016-2021 ($ Millions)

Figure 33. Middle East & Africa Plasminogen Sales 2016-2021 (MT)

Figure 34. Middle East & Africa Plasminogen Revenue 2016-2021 ($ Millions)

Figure 35. Americas Plasminogen Sales Market Share by Country in 2020

Figure 36. Americas Plasminogen Revenue Market Share by Country in 2020

Figure 37. Americas Plasminogen Sales Market Share by Type in 2020

Figure 38. Americas Plasminogen Sales Market Share by Application in 2020

Figure 39. United States Plasminogen Revenue Growth 2016-2021 ($ Millions)

Figure 40. Canada Plasminogen Revenue Growth 2016-2021 ($ Millions)

Figure 41. Mexico Plasminogen Revenue Growth 2016-2021 ($ Millions)

Figure 42. Brazil Plasminogen Revenue Growth 2016-2021 ($ Millions)

Figure 43. APAC Plasminogen Sales Market Share by Region in 2020

Figure 44. APAC Plasminogen Revenue Market Share by Regions in 2020

Figure 45. APAC Plasminogen Sales Market Share by Type in 2020

Figure 46. APAC Plasminogen Sales Market Share by Application in 2020

Figure 47. China Plasminogen Revenue Growth 2016-2021 ($ Millions)

Figure 48. Japan Plasminogen Revenue Growth 2016-2021 ($ Millions)

Figure 49. Korea Plasminogen Revenue Growth 2016-2021 ($ Millions)

Figure 50. Southeast Asia Plasminogen Revenue Growth 2016-2021 ($ Millions)

Figure 51. India Plasminogen Revenue Growth 2016-2021 ($ Millions)

Figure 52. Australia Plasminogen Revenue Growth 2016-2021 ($ Millions)

Figure 53. Europe Plasminogen Sales Market Share by Country in 2020

Figure 54. Europe Plasminogen Revenue Market Share by Country in 2020

Figure 55. Europe Plasminogen Sales Market Share by Type in 2020

Figure 56. Europe Plasminogen Sales Market Share by Application in 2020

Figure 57. Germany Plasminogen Revenue Growth 2016-2021 ($ Millions)

Figure 58. France Plasminogen Revenue Growth 2016-2021 ($ Millions)

Figure 59. UK Plasminogen Revenue Growth 2016-2021 ($ Millions)

Figure 60. Italy Plasminogen Revenue Growth 2016-2021 ($ Millions)

Figure 61. Russia Plasminogen Revenue Growth 2016-2021 ($ Millions)

Figure 62. Middle East & Africa Plasminogen Sales Market Share by Country in 2020

Figure 63. Middle East & Africa Plasminogen Revenue Market Share by Country in 2020

Figure 64. Middle East & Africa Plasminogen Sales Market Share by Type in 2020

Figure 65. Middle East & Africa Plasminogen Sales Market Share by Application in 2020

Figure 66. Egypt Plasminogen Revenue Growth 2016-2021 ($ Millions)

Figure 67. South Africa Plasminogen Revenue Growth 2016-2021 ($ Millions)

Figure 68. Israel Plasminogen Revenue Growth 2016-2021 ($ Millions)

Figure 69. Turkey Plasminogen Revenue Growth 2016-2021 ($ Millions)

Figure 70. GCC Country Plasminogen Revenue Growth 2016-2021 ($ Millions)

Figure 71. Channels of Distribution

Figure 72. Distributors Profiles

Sample Request is not available